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Are bioinformatics questions on-topic on this forum?

Or is there a .stackexchange forum more dedicated to bioinformatics?

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I don't see a Stack Exchange site currently dedicated to bioinformatics. Bioinformatics should be on-topic here, since it is computational, and it shares some methods with statistics and machine learning. I think as long as the questions are more about computatjional methods and less about biology, it could work well. A challenge we face as an interdisciplinary community is getting enough experts to contribute both questions and answers when new topics come up. Computational chemistry is on-topic, for instance, but most of those questions have migrated to Chemistry Stack Exchange; you might try looking at Biology Stack Exchange to see if they have a community of bioinformaticians.

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We accept bioinformatics questions in BiologySE given that they are not really about coding. See here. For coding stackoverflow would be the appropriate site.

You may also want to have a look at Biostars (which is modeled on SE 1.0 but not a part of stackexchange)

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